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SMILES: Cc1csc2c(OCc3cccc(Cl)c3)nc(nc12)N1CCNCC1

InChI Key: InChIKey=NCLOHNXLXINZQJ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50304825   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50304825
PNG
(4-(3-chlorobenzyloxy)-7-methyl-2-(piperazin-1-yl)t...)
Show SMILES Cc1csc2c(OCc3cccc(Cl)c3)nc(nc12)N1CCNCC1
Show InChI InChI=1S/C18H19ClN4OS/c1-12-11-25-16-15(12)21-18(23-7-5-20-6-8-23)22-17(16)24-10-13-3-2-4-14(19)9-13/h2-4,9,11,20H,5-8,10H2,1H3
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n/an/a 126n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Antagonist activity against human 5HT2C receptor by FLIPR assay

Bioorg Med Chem Lett 20: 266-71 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.112
BindingDB Entry DOI: 10.7270/Q2154H5M
More data for this
Ligand-Target Pair