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SMILES: CCS(=O)(=O)Nc1cccc(c1)-c1c(-c2ccc3nccnc3c2)n(C)n(C)c1=O

InChI Key: InChIKey=XATUEUOSZDGHLZ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50304867   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
TGF-beta receptor type-1


(Homo sapiens (Human))		BDBM50304867
PNG
(CHEMBL594409 | N-(3-(1,2-dimethyl-3-oxo-5-(quinoxa...)
Show SMILES CCS(=O)(=O)Nc1cccc(c1)-c1c(-c2ccc3nccnc3c2)n(C)n(C)c1=O
Show InChI InChI=1S/C21H21N5O3S/c1-4-30(28,29)24-16-7-5-6-14(12-16)19-20(25(2)26(3)21(19)27)15-8-9-17-18(13-15)23-11-10-22-17/h5-13,24H,4H2,1-3H3
PDB
MMDB

UniProtKB/SwissProt

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antibodypedia
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PC cid
PC sid
UniChem

Similars
Article
PubMed
>2.80E+6n/an/an/an/an/an/an/an/a



Biogen Idec Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]HTS446284 from human recombinant His-tagged TGFbetaR1 after 1 hr by scintillation counting

Bioorg Med Chem Lett 20: 326-9 (2010)


Article DOI: 10.1016/j.bmcl.2009.10.108
BindingDB Entry DOI: 10.7270/Q2RN37ZK
More data for this
Ligand-Target Pair