BDBM50305029 (6-(3-chlorophenylamino)pyridin-3-yl)(piperidin-1-yl)methanone::CHEMBL595932

SMILES: Clc1cccc(Nc2ccc(cn2)C(=O)N2CCCCC2)c1

InChI Key: InChIKey=XNDWKUXGHHKXDO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50305029   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50305029 ((6-(3-chlorophenylamino)pyridin-3-yl)(piperidin-1-...) Show SMILES Clc1cccc(Nc2ccc(cn2)C(=O)N2CCCCC2)c1 Show InChI InChI=1S/C17H18ClN3O/c18-14-5-4-6-15(11-14)20-16-8-7-13(12-19-16)17(22)21-9-2-1-3-10-21/h4-8,11-12H,1-3,9-10H2,(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Antagonist activity at human mGluR5 assessed as inhibition of glutamate-induced elevation of intracellular calcium concentration				Bioorg Med Chem Lett 20: 184-8 (2010) Article DOI: 10.1016/j.bmcl.2009.11.001 BindingDB Entry DOI: 10.7270/Q2QN66VN
					More data for this Ligand-Target Pair