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SMILES: CN1CCC2C(C1)c1cc(F)ccc1N2\C=C\c1ccccc1

InChI Key: InChIKey=YAXXEHSATLOCBK-FMIVXFBMSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50305250   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 6


(Homo sapiens (Human))		BDBM50305250
PNG
(8-Fluoro-2-methyl-5-((E)-styryl)-2,3,4,5-tetrahydr...)
Show SMILES CN1CCC2C(C1)c1cc(F)ccc1N2\C=C\c1ccccc1
Show InChI InChI=1S/C20H21FN2/c1-22-11-10-20-18(14-22)17-13-16(21)7-8-19(17)23(20)12-9-15-5-3-2-4-6-15/h2-9,12-13,18,20H,10-11,14H2,1H3/b12-9+
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Article
PubMed
n/an/a 1.75E+3n/an/an/an/an/an/a



Chemical Diversity Research Institute

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant 5HT6 receptor expressed in HEK-293 cells assessed as inhibition of serotonin-induced increase in intracellul...

Bioorg Med Chem Lett 20: 78-82 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.037
BindingDB Entry DOI: 10.7270/Q25Q4W6C
More data for this
Ligand-Target Pair