BDBM50305406 1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-(cyanomethyl)-N-(2-(piperidin-1-yl)ethyl)-1H-pyrazole-3-carboxamide::CHEMBL589159

SMILES: Clc1ccc(cc1)-c1c(CC#N)c(nn1-c1ccccc1Cl)C(=O)NCCN1CCCCC1

InChI Key: InChIKey=KHAAKYNGKAYXSE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50305406   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50305406 (1-(2-chlorophenyl)-5-(4-chlorophenyl)-4-(cyanometh...) Show SMILES Clc1ccc(cc1)-c1c(CC#N)c(nn1-c1ccccc1Cl)C(=O)NCCN1CCCCC1 Show InChI InChI=1S/C25H25Cl2N5O/c26-19-10-8-18(9-11-19)24-20(12-13-28)23(30-32(24)22-7-3-2-6-21(22)27)25(33)29-14-17-31-15-4-1-5-16-31/h2-3,6-11H,1,4-5,12,14-17H2,(H,29,33)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.11E+3	n/a	n/a	n/a	n/a	n/a	n/a
7TM Pharma A/S Curated by ChEMBL					Assay Description Antagonist activity at human recombinant CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940-stimulated GTPgammaS binding				Bioorg Med Chem Lett 20: 26-30 (2010) Article DOI: 10.1016/j.bmcl.2009.11.047 BindingDB Entry DOI: 10.7270/Q28G8KS9
					More data for this Ligand-Target Pair