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SMILES: Clc1ccc(cc1)-c1c(CC#N)c(nn1-c1ccccc1Cl)C(=O)N1Cc2ccc(Br)cc2C1

InChI Key: InChIKey=KEMWCCPIKZIGDG-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50305440   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cannabinoid receptor 1


(Homo sapiens (Human))		BDBM50305440
PNG
(2-(3-(5-bromoisoindoline-2-carbonyl)-1-(2-chloroph...)
Show SMILES Clc1ccc(cc1)-c1c(CC#N)c(nn1-c1ccccc1Cl)C(=O)N1Cc2ccc(Br)cc2C1
Show InChI InChI=1S/C26H17BrCl2N4O/c27-19-8-5-17-14-32(15-18(17)13-19)26(34)24-21(11-12-30)25(16-6-9-20(28)10-7-16)33(31-24)23-4-2-1-3-22(23)29/h1-10,13H,11,14-15H2
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Similars
Article
PubMed
n/an/a 0.220n/an/an/an/an/an/a



7TM Pharma A/S

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP55940-stimulated GTPgammaS binding

Bioorg Med Chem Lett 20: 26-30 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.047
BindingDB Entry DOI: 10.7270/Q28G8KS9
More data for this
Ligand-Target Pair