BDBM50305490 8-methyl-4-(3-(3-(methylsulfonyl)phenoxy)phenyl)quinoline-3-carboxamide::CHEMBL604259
SMILES: Cc1cccc2c(-c3cccc(Oc4cccc(c4)S(C)(=O)=O)c3)c(cnc12)C(N)=O
InChI Key: InChIKey=XBDCCVVGSIGGTL-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Oxysterols receptor LXR-alpha (Homo sapiens (Human)) | BDBM50305490 (8-methyl-4-(3-(3-(methylsulfonyl)phenoxy)phenyl)qu...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 756 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Pharmaceuticals Curated by ChEMBL | Assay Description Displacement of [3H]TO901317 from human recombinant LXRalpha expressed in Escherichia coli by flashplate method | Bioorg Med Chem Lett 20: 689-93 (2010) Article DOI: 10.1016/j.bmcl.2009.11.062 BindingDB Entry DOI: 10.7270/Q2W66KV8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oxysterols receptor LXR-beta (Homo sapiens (Human)) | BDBM50305490 (8-methyl-4-(3-(3-(methylsulfonyl)phenoxy)phenyl)qu...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Pharmaceuticals Curated by ChEMBL | Assay Description Displacement of [3H]TO901317 from human recombinant LXRbeta expressed in Escherichia coli by flashplate method | Bioorg Med Chem Lett 20: 689-93 (2010) Article DOI: 10.1016/j.bmcl.2009.11.062 BindingDB Entry DOI: 10.7270/Q2W66KV8 | |||||||||||
More data for this Ligand-Target Pair |