BDBM50305634 CHEMBL589375::N-(2,4-dichlorobenzyl)-4-(4-(trifluoromethoxy)phenoxy)piperidine-1-carboxamide

SMILES: FC(F)(F)Oc1ccc(OC2CCN(CC2)C(=O)NCc2ccc(Cl)cc2Cl)cc1

InChI Key: InChIKey=KXSZHUYAHSPJGP-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50305634   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
EBifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50305634 (CHEMBL589375 | N-(2,4-dichlorobenzyl)-4-(4-(triflu...) Show SMILES FC(F)(F)Oc1ccc(OC2CCN(CC2)C(=O)NCc2ccc(Cl)cc2Cl)cc1 Show InChI InChI=1S/C20H19Cl2F3N2O3/c21-14-2-1-13(18(22)11-14)12-26-19(28)27-9-7-16(8-10-27)29-15-3-5-17(6-4-15)30-20(23,24)25/h1-6,11,16H,7-10,12H2,(H,26,28)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	18	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human soluble epoxide hydrolase in human HepG cells assessed as conversion of epoxyeicosatienoic acid to dihydroxyeicosatrienoic acid a...				Bioorg Med Chem Lett 20: 571-5 (2010) Article DOI: 10.1016/j.bmcl.2009.11.091 BindingDB Entry DOI: 10.7270/Q23R0SZ6
					More data for this Ligand-Target Pair
EBifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50305634 (CHEMBL589375 | N-(2,4-dichlorobenzyl)-4-(4-(triflu...) Show SMILES FC(F)(F)Oc1ccc(OC2CCN(CC2)C(=O)NCc2ccc(Cl)cc2Cl)cc1 Show InChI InChI=1S/C20H19Cl2F3N2O3/c21-14-2-1-13(18(22)11-14)12-26-19(28)27-9-7-16(8-10-27)29-15-3-5-17(6-4-15)30-20(23,24)25/h1-6,11,16H,7-10,12H2,(H,26,28)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of rhodamine-labeled probe from human soluble epoxide hydrolase by fluorescence polarization assay				Bioorg Med Chem Lett 20: 571-5 (2010) Article DOI: 10.1016/j.bmcl.2009.11.091 BindingDB Entry DOI: 10.7270/Q23R0SZ6
					More data for this Ligand-Target Pair