BDBM50305654 4-(2-(furan-3-yl)-9H-purin-6-yl)morpholine::CHEMBL593514

SMILES: C1CN(CCO1)c1nc(nc2nc[nH]c12)-c1ccoc1

InChI Key: InChIKey=YMMOIRWTLTTWOB-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50305654   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50305654 (4-(2-(furan-3-yl)-9H-purin-6-yl)morpholine | CHEMB...) Show SMILES C1CN(CCO1)c1nc(nc2nc[nH]c12)-c1ccoc1 Show InChI InChI=1S/C13H13N5O2/c1-4-20-7-9(1)11-16-12-10(14-8-15-12)13(17-11)18-2-5-19-6-3-18/h1,4,7-8H,2-3,5-6H2,(H,14,15,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of GST-GRP1-fused PI3Kgamma by microtiter plate based fluorescence polarization assay				Bioorg Med Chem Lett 20: 636-9 (2010) Article DOI: 10.1016/j.bmcl.2009.11.051 BindingDB Entry DOI: 10.7270/Q2V98852
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50305654 (4-(2-(furan-3-yl)-9H-purin-6-yl)morpholine | CHEMB...) Show SMILES C1CN(CCO1)c1nc(nc2nc[nH]c12)-c1ccoc1 Show InChI InChI=1S/C13H13N5O2/c1-4-20-7-9(1)11-16-12-10(14-8-15-12)13(17-11)18-2-5-19-6-3-18/h1,4,7-8H,2-3,5-6H2,(H,14,15,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.79E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of GST-GRP1-fused PI3Kalpha by microtiter plate based fluorescence polarization assay				Bioorg Med Chem Lett 20: 636-9 (2010) Article DOI: 10.1016/j.bmcl.2009.11.051 BindingDB Entry DOI: 10.7270/Q2V98852
					More data for this Ligand-Target Pair