BDBM50305729 6-(2,4-difluorobenzyl)-3-isopropyl-1,8a-dihydro-[1,2,4]triazolo[4,3-a]pyridine::CHEMBL607557
SMILES: CC(C)c1nnc2CCC(Cc3ccc(F)cc3F)=Cn12
InChI Key: InChIKey=YRPJIXXEFSPLAG-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM50305729 (6-(2,4-difluorobenzyl)-3-isopropyl-1,8a-dihydro-[1...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 26.1 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of p38 alpha | Bioorg Med Chem Lett 20: 469-73 (2010) Article DOI: 10.1016/j.bmcl.2009.11.114 BindingDB Entry DOI: 10.7270/Q2G160XP | |||||||||||
More data for this Ligand-Target Pair |