BDBM50305741 1,4-ditosylpiperazine::CHEMBL596080
SMILES: Cc1ccc(cc1)S(=O)(=O)N1CCN(CC1)S(=O)(=O)c1ccc(C)cc1
InChI Key: InChIKey=LMIXCJFVEQOWSQ-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human)) | BDBM50305741 (1,4-ditosylpiperazine | CHEMBL596080) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >6.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Antagonist activity at human C5a receptor expressed in CHO cells co-expressed with Galpha16 assessed as inhibition of anaphylatoxin C5a-induced intra... | Bioorg Med Chem Lett 20: 662-4 (2010) Article DOI: 10.1016/j.bmcl.2009.11.058 BindingDB Entry DOI: 10.7270/Q2B8586C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor (C5aR) (Homo sapiens (Human)) | BDBM50305741 (1,4-ditosylpiperazine | CHEMBL596080) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >6.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description Antagonist activity at C5a receptor in human PMNC assessed as inhibition of anaphylatoxin C5a-induced intracellular calcium accumulation after 10 min... | Bioorg Med Chem Lett 20: 662-4 (2010) Article DOI: 10.1016/j.bmcl.2009.11.058 BindingDB Entry DOI: 10.7270/Q2B8586C | |||||||||||
More data for this Ligand-Target Pair |