BDBM50305753 3-(4-(2,3-dihydro-1H-inden-5-yloxy)piperidin-1-yl)-6-(1H-imidazol-1-yl)pyridazine::CHEMBL603324

SMILES: C1Cc2ccc(OC3CCN(CC3)c3ccc(nn3)-n3ccnc3)cc2C1

InChI Key: InChIKey=RPJIPIUBJDHTJN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50305753   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Stearoyl-CoA desaturase 1 (SCD1) (Rattus norvegicus (Rat))	BDBM50305753 (3-(4-(2,3-dihydro-1H-inden-5-yloxy)piperidin-1-yl)...) Show SMILES C1Cc2ccc(OC3CCN(CC3)c3ccc(nn3)-n3ccnc3)cc2C1 Show InChI InChI=1S/C21H23N5O/c1-2-16-4-5-19(14-17(16)3-1)27-18-8-11-25(12-9-18)20-6-7-21(24-23-20)26-13-10-22-15-26/h4-7,10,13-15,18H,1-3,8-9,11-12H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	62	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibition of SCD1 in rat liver microsomes				Bioorg Med Chem Lett 20: 499-502 (2010) Article DOI: 10.1016/j.bmcl.2009.11.111 BindingDB Entry DOI: 10.7270/Q26H4HH3
					More data for this Ligand-Target Pair