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SMILES: CC(C)(C)[C@H](C(=O)Nc1ncc(s1)N1CCOCC1)c1ccc(Cl)cc1

InChI Key: InChIKey=RMKYWYVUNRDOEM-INIZCTEOSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50305914   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Free fatty acid receptor 2


(Homo sapiens (Human))		BDBM50305914
PNG
((S)-2-(4-chlorophenyl)-3,3-dimethyl-N-(5-morpholin...)
Show SMILES CC(C)(C)[C@H](C(=O)Nc1ncc(s1)N1CCOCC1)c1ccc(Cl)cc1 |r|
Show InChI InChI=1S/C19H24ClN3O2S/c1-19(2,3)16(13-4-6-14(20)7-5-13)17(24)22-18-21-12-15(26-18)23-8-10-25-11-9-23/h4-7,12,16H,8-11H2,1-3H3,(H,21,22,24)/t16-/m0/s1
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Article
PubMed
n/an/a 1.60E+3n/an/an/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production

Bioorg Med Chem Lett 20: 493-8 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.112
BindingDB Entry DOI: 10.7270/Q21V5F2Q
More data for this
Ligand-Target Pair