BindingDB logo
myBDB logout

null

SMILES: CC(C)(C)[C@H](C(=O)Nc1ncc(s1)N1CCS(=O)(=O)CC1)c1ccc(Cl)cc1

InChI Key: InChIKey=JIGYQRKEQHMNGA-INIZCTEOSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50305916   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Free fatty acid receptor 2


(Homo sapiens (Human))		BDBM50305916
PNG
((S)-2-(4-Chloro-phenyl)-N-[5-(1,1-dioxo-1lambda*6*...)
Show SMILES CC(C)(C)[C@H](C(=O)Nc1ncc(s1)N1CCS(=O)(=O)CC1)c1ccc(Cl)cc1 |r|
Show InChI InChI=1S/C19H24ClN3O3S2/c1-19(2,3)16(13-4-6-14(20)7-5-13)17(24)22-18-21-12-15(27-18)23-8-10-28(25,26)11-9-23/h4-7,12,16H,8-11H2,1-3H3,(H,21,22,24)/t16-/m0/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.40E+3n/an/an/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Agonist activity at human FFA2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP production

Bioorg Med Chem Lett 20: 493-8 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.112
BindingDB Entry DOI: 10.7270/Q21V5F2Q
More data for this
Ligand-Target Pair