BDBM50306074 2-(4-fluorobenzyl)-1-(3-(3-(methylsulfonyl)phenoxy)phenyl)-4-(trifluoromethyl)-1H-benzo[d]imidazole::CHEMBL594062

SMILES: CS(=O)(=O)c1cccc(Oc2cccc(c2)-n2c(Cc3ccc(F)cc3)nc3c(cccc23)C(F)(F)F)c1

InChI Key: InChIKey=MFDLTITVUNIPCT-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50306074   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Oxysterols receptor LXR-alpha (Homo sapiens (Human))	BDBM50306074 (2-(4-fluorobenzyl)-1-(3-(3-(methylsulfonyl)phenoxy...) Show SMILES CS(=O)(=O)c1cccc(Oc2cccc(c2)-n2c(Cc3ccc(F)cc3)nc3c(cccc23)C(F)(F)F)c1 Show InChI InChI=1S/C28H20F4N2O3S/c1-38(35,36)23-8-3-7-22(17-23)37-21-6-2-5-20(16-21)34-25-10-4-9-24(28(30,31)32)27(25)33-26(34)15-18-11-13-19(29)14-12-18/h2-14,16-17H,15H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]T0901317 from human recombinant LXRalpha LBD				Bioorg Med Chem Lett 20: 526-30 (2010) Article DOI: 10.1016/j.bmcl.2009.11.099 BindingDB Entry DOI: 10.7270/Q2HT2PDZ
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM50306074 (2-(4-fluorobenzyl)-1-(3-(3-(methylsulfonyl)phenoxy...) Show SMILES CS(=O)(=O)c1cccc(Oc2cccc(c2)-n2c(Cc3ccc(F)cc3)nc3c(cccc23)C(F)(F)F)c1 Show InChI InChI=1S/C28H20F4N2O3S/c1-38(35,36)23-8-3-7-22(17-23)37-21-6-2-5-20(16-21)34-25-10-4-9-24(28(30,31)32)27(25)33-26(34)15-18-11-13-19(29)14-12-18/h2-14,16-17H,15H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]T0901317 from human recombinant LXRbeta LBD				Bioorg Med Chem Lett 20: 526-30 (2010) Article DOI: 10.1016/j.bmcl.2009.11.099 BindingDB Entry DOI: 10.7270/Q2HT2PDZ
					More data for this Ligand-Target Pair