BDBM50306077 1-(2-chloro-5-(3-(ethylsulfonyl)phenoxy)phenyl)-4-(trifluoromethyl)-1H-benzo[d]imidazole::CHEMBL594367

SMILES: CCS(=O)(=O)c1cccc(Oc2ccc(Cl)c(c2)-n2cnc3c(cccc23)C(F)(F)F)c1

InChI Key: InChIKey=INTBHOCJAASBMR-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50306077   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Oxysterols receptor LXR-alpha (Homo sapiens (Human))	BDBM50306077 (1-(2-chloro-5-(3-(ethylsulfonyl)phenoxy)phenyl)-4-...) Show SMILES CCS(=O)(=O)c1cccc(Oc2ccc(Cl)c(c2)-n2cnc3c(cccc23)C(F)(F)F)c1 Show InChI InChI=1S/C22H16ClF3N2O3S/c1-2-32(29,30)16-6-3-5-14(11-16)31-15-9-10-18(23)20(12-15)28-13-27-21-17(22(24,25)26)7-4-8-19(21)28/h3-13H,2H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]T0901317 from human recombinant LXRalpha LBD				Bioorg Med Chem Lett 20: 526-30 (2010) Article DOI: 10.1016/j.bmcl.2009.11.099 BindingDB Entry DOI: 10.7270/Q2HT2PDZ
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM50306077 (1-(2-chloro-5-(3-(ethylsulfonyl)phenoxy)phenyl)-4-...) Show SMILES CCS(=O)(=O)c1cccc(Oc2ccc(Cl)c(c2)-n2cnc3c(cccc23)C(F)(F)F)c1 Show InChI InChI=1S/C22H16ClF3N2O3S/c1-2-32(29,30)16-6-3-5-14(11-16)31-15-9-10-18(23)20(12-15)28-13-27-21-17(22(24,25)26)7-4-8-19(21)28/h3-13H,2H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]T0901317 from human recombinant LXRbeta LBD				Bioorg Med Chem Lett 20: 526-30 (2010) Article DOI: 10.1016/j.bmcl.2009.11.099 BindingDB Entry DOI: 10.7270/Q2HT2PDZ
					More data for this Ligand-Target Pair