BDBM50306083 4-chloro-1-(2-chloro-5-(3-(trifluoromethylsulfonyl)phenoxy)phenyl)-2-methyl-1H-benzo[d]imidazole::CHEMBL605723

SMILES: Cc1nc2c(Cl)cccc2n1-c1cc(Oc2cccc(c2)S(=O)(=O)C(F)(F)F)ccc1Cl

InChI Key: InChIKey=NKFCIEVAMLCUCO-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50306083   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Oxysterols receptor LXR-alpha (Homo sapiens (Human))	BDBM50306083 (4-chloro-1-(2-chloro-5-(3-(trifluoromethylsulfonyl...) Show SMILES Cc1nc2c(Cl)cccc2n1-c1cc(Oc2cccc(c2)S(=O)(=O)C(F)(F)F)ccc1Cl |(40.06,-46.33,;38.52,-46.33,;37.61,-47.58,;36.15,-47.1,;34.82,-47.88,;34.82,-49.42,;33.48,-47.11,;33.49,-45.57,;34.81,-44.8,;36.15,-45.56,;37.61,-45.09,;37.6,-43.54,;38.93,-42.76,;38.92,-41.22,;40.25,-40.44,;41.58,-41.2,;41.59,-42.73,;42.93,-43.49,;44.26,-42.71,;44.24,-41.16,;42.9,-40.41,;45.56,-40.37,;46.64,-39.28,;44.46,-39.28,;46.88,-41.14,;48.22,-40.38,;46.88,-42.68,;48.37,-41.54,;37.57,-40.46,;36.24,-41.25,;36.26,-42.79,;34.94,-43.58,)| Show InChI InChI=1S/C21H13Cl2F3N2O3S/c1-12-27-20-17(23)6-3-7-18(20)28(12)19-11-14(8-9-16(19)22)31-13-4-2-5-15(10-13)32(29,30)21(24,25)26/h2-11H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]T0901317 from human recombinant LXRalpha LBD				Bioorg Med Chem Lett 20: 526-30 (2010) Article DOI: 10.1016/j.bmcl.2009.11.099 BindingDB Entry DOI: 10.7270/Q2HT2PDZ
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Homo sapiens (Human))	BDBM50306083 (4-chloro-1-(2-chloro-5-(3-(trifluoromethylsulfonyl...) Show SMILES Cc1nc2c(Cl)cccc2n1-c1cc(Oc2cccc(c2)S(=O)(=O)C(F)(F)F)ccc1Cl |(40.06,-46.33,;38.52,-46.33,;37.61,-47.58,;36.15,-47.1,;34.82,-47.88,;34.82,-49.42,;33.48,-47.11,;33.49,-45.57,;34.81,-44.8,;36.15,-45.56,;37.61,-45.09,;37.6,-43.54,;38.93,-42.76,;38.92,-41.22,;40.25,-40.44,;41.58,-41.2,;41.59,-42.73,;42.93,-43.49,;44.26,-42.71,;44.24,-41.16,;42.9,-40.41,;45.56,-40.37,;46.64,-39.28,;44.46,-39.28,;46.88,-41.14,;48.22,-40.38,;46.88,-42.68,;48.37,-41.54,;37.57,-40.46,;36.24,-41.25,;36.26,-42.79,;34.94,-43.58,)| Show InChI InChI=1S/C21H13Cl2F3N2O3S/c1-12-27-20-17(23)6-3-7-18(20)28(12)19-11-14(8-9-16(19)22)31-13-4-2-5-15(10-13)32(29,30)21(24,25)26/h2-11H,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	85	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]T0901317 from human recombinant LXRbeta LBD				Bioorg Med Chem Lett 20: 526-30 (2010) Article DOI: 10.1016/j.bmcl.2009.11.099 BindingDB Entry DOI: 10.7270/Q2HT2PDZ
					More data for this Ligand-Target Pair