null

SMILES: Cc1n[nH]c2ccc(cc12)-c1cc(OC[C@@H](N)Cc2ccccc2)cnc1-c1ccccc1O

InChI Key: InChIKey=NXALXNCWSLFUIV-NRFANRHFSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50306089   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM50306089 (2-(5-((S)-2-amino-3-phenylpropoxy)-3-(3-methyl-1H-...) Show SMILES Cc1n[nH]c2ccc(cc12)-c1cc(OC[C@@H](N)Cc2ccccc2)cnc1-c1ccccc1O |r| Show InChI InChI=1S/C28H26N4O2/c1-18-24-14-20(11-12-26(24)32-31-18)25-15-22(16-30-28(25)23-9-5-6-10-27(23)33)34-17-21(29)13-19-7-3-2-4-8-19/h2-12,14-16,21,33H,13,17,29H2,1H3,(H,31,32)/t21-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of ROCK1				Bioorg Med Chem Lett 20: 673-8 (2010) Article DOI: 10.1016/j.bmcl.2009.11.064 BindingDB Entry DOI: 10.7270/Q2D21XQ0
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50306089 (2-(5-((S)-2-amino-3-phenylpropoxy)-3-(3-methyl-1H-...) Show SMILES Cc1n[nH]c2ccc(cc12)-c1cc(OC[C@@H](N)Cc2ccccc2)cnc1-c1ccccc1O |r| Show InChI InChI=1S/C28H26N4O2/c1-18-24-14-20(11-12-26(24)32-31-18)25-15-22(16-30-28(25)23-9-5-6-10-27(23)33)34-17-21(29)13-19-7-3-2-4-8-19/h2-12,14-16,21,33H,13,17,29H2,1H3,(H,31,32)/t21-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of full length AKT1				Bioorg Med Chem Lett 20: 673-8 (2010) Article DOI: 10.1016/j.bmcl.2009.11.064 BindingDB Entry DOI: 10.7270/Q2D21XQ0
					More data for this Ligand-Target Pair