BDBM50306091 (S)-1-(6-(furan-3-yl)-5-(3-methyl-1H-indazol-5-yl)pyridin-3-yloxy)-3-(1H-pyrrolo[3,2-c]pyridin-3-yl)propan-2-amine::CHEMBL593142

SMILES: Cc1n[nH]c2ccc(cc12)-c1cc(OC[C@@H](N)Cc2c[nH]c3ccncc23)cnc1-c1ccoc1

InChI Key: InChIKey=MFRVBNSUIBWIRX-FQEVSTJZSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50306091   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50306091 ((S)-1-(6-(furan-3-yl)-5-(3-methyl-1H-indazol-5-yl)...) Show SMILES Cc1n[nH]c2ccc(cc12)-c1cc(OC[C@@H](N)Cc2c[nH]c3ccncc23)cnc1-c1ccoc1 |r| Show InChI InChI=1S/C27H24N6O2/c1-16-22-9-17(2-3-26(22)33-32-16)23-10-21(12-31-27(23)18-5-7-34-14-18)35-15-20(28)8-19-11-30-25-4-6-29-13-24(19)25/h2-7,9-14,20,30H,8,15,28H2,1H3,(H,32,33)/t20-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of full length AKT1				Bioorg Med Chem Lett 20: 673-8 (2010) Article DOI: 10.1016/j.bmcl.2009.11.064 BindingDB Entry DOI: 10.7270/Q2D21XQ0
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50306091 ((S)-1-(6-(furan-3-yl)-5-(3-methyl-1H-indazol-5-yl)...) Show SMILES Cc1n[nH]c2ccc(cc12)-c1cc(OC[C@@H](N)Cc2c[nH]c3ccncc23)cnc1-c1ccoc1 |r| Show InChI InChI=1S/C27H24N6O2/c1-16-22-9-17(2-3-26(22)33-32-16)23-10-21(12-31-27(23)18-5-7-34-14-18)35-15-20(28)8-19-11-30-25-4-6-29-13-24(19)25/h2-7,9-14,20,30H,8,15,28H2,1H3,(H,32,33)/t20-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of AKT1 in human BT474 cells assessed as phosphorylation of GSK3				Bioorg Med Chem Lett 20: 673-8 (2010) Article DOI: 10.1016/j.bmcl.2009.11.064 BindingDB Entry DOI: 10.7270/Q2D21XQ0
					More data for this Ligand-Target Pair