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SMILES: CC(N(C)C)c1ccc(N2CC[C@H](NS(=O)(=O)c3cc4ccc(Cl)cc4s3)C2=O)c(F)c1

InChI Key: InChIKey=LAFMSVDAYLPWTK-UWBLVGDVSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50306145   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))		BDBM50306145
PNG
(6-chloro-N-((3S)-1-(4-(1-(dimethylamino)ethyl)-2-f...)
Show SMILES CC(N(C)C)c1ccc(N2CC[C@H](NS(=O)(=O)c3cc4ccc(Cl)cc4s3)C2=O)c(F)c1 |r|
Show InChI InChI=1S/C22H23ClFN3O3S2/c1-13(26(2)3)14-5-7-19(17(24)10-14)27-9-8-18(22(27)28)25-32(29,30)21-11-15-4-6-16(23)12-20(15)31-21/h4-7,10-13,18,25H,8-9H2,1-3H3/t13?,18-/m0/s1
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 5n/an/an/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibition of human factor 10a by fluorescence assay

Bioorg Med Chem Lett 20: 618-22 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.077
BindingDB Entry DOI: 10.7270/Q24M94NN
More data for this
Ligand-Target Pair