BDBM50306152 (S)-2-(5-chlorothiophen-2-yl)-N-(1-(2-fluoro-4-(prop-1-en-2-yl)phenyl)-2-oxopyrrolidin-3-yl)ethenesulfonamide::CHEMBL594085

SMILES: CC(=C)c1ccc(N2CC[C@H](NS(=O)(=O)\C=C\c3ccc(Cl)s3)C2=O)c(F)c1

InChI Key: InChIKey=NNZZXQHYOLMHKT-DZZUKKPASA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50306152   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50306152 ((S)-2-(5-chlorothiophen-2-yl)-N-(1-(2-fluoro-4-(pr...) Show SMILES CC(=C)c1ccc(N2CC[C@H](NS(=O)(=O)\C=C\c3ccc(Cl)s3)C2=O)c(F)c1 |r| Show InChI InChI=1S/C19H18ClFN2O3S2/c1-12(2)13-3-5-17(15(21)11-13)23-9-7-16(19(23)24)22-28(25,26)10-8-14-4-6-18(20)27-14/h3-6,8,10-11,16,22H,1,7,9H2,2H3/b10-8+/t16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human factor 10a by fluorescence assay				Bioorg Med Chem Lett 20: 618-22 (2010) Article DOI: 10.1016/j.bmcl.2009.11.077 BindingDB Entry DOI: 10.7270/Q24M94NN
					More data for this Ligand-Target Pair