BDBM50306203 2-(4-(1,4-diazepane-1-carbonyl)phenyl)-2H-indazole-7-carboxamide::CHEMBL596143

SMILES: NC(=O)c1cccc2cn(nc12)-c1ccc(cc1)C(=O)N1CCCNCC1

InChI Key: InChIKey=PDRUYQAWRBGOQZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50306203   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50306203 (2-(4-(1,4-diazepane-1-carbonyl)phenyl)-2H-indazole...) Show SMILES NC(=O)c1cccc2cn(nc12)-c1ccc(cc1)C(=O)N1CCCNCC1 Show InChI InChI=1S/C20H21N5O2/c21-19(26)17-4-1-3-15-13-25(23-18(15)17)16-7-5-14(6-8-16)20(27)24-11-2-9-22-10-12-24/h1,3-8,13,22H,2,9-12H2,(H2,21,26)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
IRBM-Merck Research Laboratories Rome Curated by ChEMBL					Assay Description Inhibition of human PARP1 after 3 hrs using [3H]NAD+ by scintillation proximity assay				Bioorg Med Chem Lett 20: 488-92 (2010) Article DOI: 10.1016/j.bmcl.2009.11.127 BindingDB Entry DOI: 10.7270/Q2W37WFZ
					More data for this Ligand-Target Pair