BDBM50306496 2-(6-chloro-5-((2R,5S)-4-(1-cyano-1-(4-fluorophenyl)ethyl)-2,5-dimethylpiperazine-1-carbonyl)-1-methyl-1H-indol-3-yl)-N,N-dimethyl-2-oxoacetamide::CHEMBL601666

SMILES: C[C@@H]1CN([C@@H](C)CN1C(=O)c1cc2c(cn(C)c2cc1Cl)C(=O)C(=O)N(C)C)C(C)(C#N)c1ccc(F)cc1

InChI Key: InChIKey=WMPPEZSRXIQKHT-YHOPASQISA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50306496   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50306496 (2-(6-chloro-5-((2R,5S)-4-(1-cyano-1-(4-fluoropheny...) Show SMILES C[C@@H]1CN([C@@H](C)CN1C(=O)c1cc2c(cn(C)c2cc1Cl)C(=O)C(=O)N(C)C)C(C)(C#N)c1ccc(F)cc1 |r| Show InChI InChI=1S/C29H31ClFN5O3/c1-17-14-36(29(3,16-32)19-7-9-20(31)10-8-19)18(2)13-35(17)27(38)22-11-21-23(26(37)28(39)33(4)5)15-34(6)25(21)12-24(22)30/h7-12,15,17-18H,13-14H2,1-6H3/t17-,18+,29?/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
Scios inc Curated by ChEMBL					Assay Description Inhibition of p38alpha				Bioorg Med Chem Lett 20: 828-31 (2010) Article DOI: 10.1016/j.bmcl.2009.12.091 BindingDB Entry DOI: 10.7270/Q22N52CF
					More data for this Ligand-Target Pair