BDBM50306510 4'-((5-(2-phenylbutanamido)-2-propyl-1H-indol-1-yl)methyl)biphenyl-2-carboxylic acid::CHEMBL601222

SMILES: CCCc1cc2cc(NC(=O)C(CC)c3ccccc3)ccc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O

InChI Key: InChIKey=WRKLSZQCSKSDIC-UHFFFAOYSA-N

Data: 3 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50306510   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50306510 (4'-((5-(2-phenylbutanamido)-2-propyl-1H-indol-1-yl...) Show SMILES CCCc1cc2cc(NC(=O)C(CC)c3ccccc3)ccc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O Show InChI InChI=1S/C35H34N2O3/c1-3-10-29-22-27-21-28(36-34(38)30(4-2)25-11-6-5-7-12-25)19-20-33(27)37(29)23-24-15-17-26(18-16-24)31-13-8-9-14-32(31)35(39)40/h5-9,11-22,30H,3-4,10,23H2,1-2H3,(H,36,38)(H,39,40)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Displacement of radiolabled GW2433 from human PPARdelta ligand binding domain expressed in Escherichia coli				Bioorg Med Chem Lett 20: 1399-404 (2010) Article DOI: 10.1016/j.bmcl.2009.12.107 BindingDB Entry DOI: 10.7270/Q2T43T5R
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM50306510 (4'-((5-(2-phenylbutanamido)-2-propyl-1H-indol-1-yl...) Show SMILES CCCc1cc2cc(NC(=O)C(CC)c3ccccc3)ccc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O Show InChI InChI=1S/C35H34N2O3/c1-3-10-29-22-27-21-28(36-34(38)30(4-2)25-11-6-5-7-12-25)19-20-33(27)37(29)23-24-15-17-26(18-16-24)31-13-8-9-14-32(31)35(39)40/h5-9,11-22,30H,3-4,10,23H2,1-2H3,(H,36,38)(H,39,40)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Displacement of radiolabled GW2433 from human PPARalpha ligand binding domain expressed in Escherichia coli				Bioorg Med Chem Lett 20: 1399-404 (2010) Article DOI: 10.1016/j.bmcl.2009.12.107 BindingDB Entry DOI: 10.7270/Q2T43T5R
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50306510 (4'-((5-(2-phenylbutanamido)-2-propyl-1H-indol-1-yl...) Show SMILES CCCc1cc2cc(NC(=O)C(CC)c3ccccc3)ccc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O Show InChI InChI=1S/C35H34N2O3/c1-3-10-29-22-27-21-28(36-34(38)30(4-2)25-11-6-5-7-12-25)19-20-33(27)37(29)23-24-15-17-26(18-16-24)31-13-8-9-14-32(31)35(39)40/h5-9,11-22,30H,3-4,10,23H2,1-2H3,(H,36,38)(H,39,40)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Agonist activity at human PPARgamma expressed in african green monkey CV1 cells by Gal4 transactivation assay				Bioorg Med Chem Lett 20: 1399-404 (2010) Article DOI: 10.1016/j.bmcl.2009.12.107 BindingDB Entry DOI: 10.7270/Q2T43T5R
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50306510 (4'-((5-(2-phenylbutanamido)-2-propyl-1H-indol-1-yl...) Show SMILES CCCc1cc2cc(NC(=O)C(CC)c3ccccc3)ccc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O Show InChI InChI=1S/C35H34N2O3/c1-3-10-29-22-27-21-28(36-34(38)30(4-2)25-11-6-5-7-12-25)19-20-33(27)37(29)23-24-15-17-26(18-16-24)31-13-8-9-14-32(31)35(39)40/h5-9,11-22,30H,3-4,10,23H2,1-2H3,(H,36,38)(H,39,40)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Displacement of radiolabled ((5-{4-[Methyl-pyridin-2yl-amino)-ethoxy]-benzyl}-thiazolidine-2,4-dione) from human PPARgamma ligand binding domain expr...				Bioorg Med Chem Lett 20: 1399-404 (2010) Article DOI: 10.1016/j.bmcl.2009.12.107 BindingDB Entry DOI: 10.7270/Q2T43T5R
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM50306510 (4'-((5-(2-phenylbutanamido)-2-propyl-1H-indol-1-yl...) Show SMILES CCCc1cc2cc(NC(=O)C(CC)c3ccccc3)ccc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O Show InChI InChI=1S/C35H34N2O3/c1-3-10-29-22-27-21-28(36-34(38)30(4-2)25-11-6-5-7-12-25)19-20-33(27)37(29)23-24-15-17-26(18-16-24)31-13-8-9-14-32(31)35(39)40/h5-9,11-22,30H,3-4,10,23H2,1-2H3,(H,36,38)(H,39,40)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Agonist activity at human PPARalpha expressed in african green monkey CV1 cells by Gal4 transactivation assay				Bioorg Med Chem Lett 20: 1399-404 (2010) Article DOI: 10.1016/j.bmcl.2009.12.107 BindingDB Entry DOI: 10.7270/Q2T43T5R
					More data for this Ligand-Target Pair