null

SMILES: CNC(=O)Nc1ccc(cc1)-c1nc(N2CC3CCC(C2)O3)c2cnn(C)c2n1

InChI Key: InChIKey=APYPCVRCUBVUDW-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50306622   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50306622 (1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-me...) Show SMILES CNC(=O)Nc1ccc(cc1)-c1nc(N2CC3CCC(C2)O3)c2cnn(C)c2n1 Show InChI InChI=1S/C20H23N7O2/c1-21-20(28)23-13-5-3-12(4-6-13)17-24-18-16(9-22-26(18)2)19(25-17)27-10-14-7-8-15(11-27)29-14/h3-6,9,14-15H,7-8,10-11H2,1-2H3,(H2,21,23,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	247	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PI3Kalpha				Bioorg Med Chem Lett 20: 1440-4 (2010) Article DOI: 10.1016/j.bmcl.2009.12.086 BindingDB Entry DOI: 10.7270/Q2S46S2T
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50306622 (1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1-me...) Show SMILES CNC(=O)Nc1ccc(cc1)-c1nc(N2CC3CCC(C2)O3)c2cnn(C)c2n1 Show InChI InChI=1S/C20H23N7O2/c1-21-20(28)23-13-5-3-12(4-6-13)17-24-18-16(9-22-26(18)2)19(25-17)27-10-14-7-8-15(11-27)29-14/h3-6,9,14-15H,7-8,10-11H2,1-2H3,(H2,21,23,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.34	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of mTOR				Bioorg Med Chem Lett 20: 1440-4 (2010) Article DOI: 10.1016/j.bmcl.2009.12.086 BindingDB Entry DOI: 10.7270/Q2S46S2T
					More data for this Ligand-Target Pair