BDBM50307025 3-(4-Acryloylpiperazin-1-yl)-5,7-dihydroxy-4-methyl-2H-chromen-2-one::CHEMBL601652

SMILES: Cc1c(N2CCN(CC2)C(=O)C=C)c(=O)oc2cc(O)cc(O)c12

InChI Key: InChIKey=JHLYNYOFTITACS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50307025   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 4 (CCR4) (Homo sapiens (Human))	BDBM50307025 (3-(4-Acryloylpiperazin-1-yl)-5,7-dihydroxy-4-methy...) Show SMILES Cc1c(N2CCN(CC2)C(=O)C=C)c(=O)oc2cc(O)cc(O)c12 Show InChI InChI=1S/C17H18N2O5/c1-3-14(22)18-4-6-19(7-5-18)16-10(2)15-12(21)8-11(20)9-13(15)24-17(16)23/h3,8-9,20-21H,1,4-7H2,2H3	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.24E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Medical Sciences and Peking Union Medical College Curated by ChEMBL					Assay Description Displacement of FITC-CKLF1-C27 from human CCR4 receptor expressed in human HEK293 cells				J Med Chem 53: 1741-54 (2010) Article DOI: 10.1021/jm901652p BindingDB Entry DOI: 10.7270/Q2Q81D6X
					More data for this Ligand-Target Pair