BDBM50307028 5,7-Dihydroxy-4-methyl-3-(4-(phenylsulfonyl)piperazin-1-yl)-2H-chromen-2-one::CHEMBL607137

SMILES: Cc1c(N2CCN(CC2)S(=O)(=O)c2ccccc2)c(=O)oc2cc(O)cc(O)c12

InChI Key: InChIKey=KGBWAZGRDVHLOV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50307028   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 4 (CCR4) (Homo sapiens (Human))	BDBM50307028 (5,7-Dihydroxy-4-methyl-3-(4-(phenylsulfonyl)pipera...) Show SMILES Cc1c(N2CCN(CC2)S(=O)(=O)c2ccccc2)c(=O)oc2cc(O)cc(O)c12 Show InChI InChI=1S/C20H20N2O6S/c1-13-18-16(24)11-14(23)12-17(18)28-20(25)19(13)21-7-9-22(10-8-21)29(26,27)15-5-3-2-4-6-15/h2-6,11-12,23-24H,7-10H2,1H3	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.04E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Medical Sciences and Peking Union Medical College Curated by ChEMBL					Assay Description Displacement of FITC-CKLF1-C27 from human CCR4 receptor expressed in human HEK293 cells				J Med Chem 53: 1741-54 (2010) Article DOI: 10.1021/jm901652p BindingDB Entry DOI: 10.7270/Q2Q81D6X
					More data for this Ligand-Target Pair