BDBM50307030 4-(5,7-Dihydroxy-4-methyl-2-oxo-2H-chromen-3-yl)-N-(4-isopropylphenyl)piperazine-1-carboxamide::CHEMBL606421

SMILES: CC(C)c1ccc(NC(=O)N2CCN(CC2)c2c(C)c3c(O)cc(O)cc3oc2=O)cc1

InChI Key: InChIKey=KKICCNGMCBHQEY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50307030   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 4 (CCR4) (Homo sapiens (Human))	BDBM50307030 (4-(5,7-Dihydroxy-4-methyl-2-oxo-2H-chromen-3-yl)-N...) Show SMILES CC(C)c1ccc(NC(=O)N2CCN(CC2)c2c(C)c3c(O)cc(O)cc3oc2=O)cc1 Show InChI InChI=1S/C24H27N3O5/c1-14(2)16-4-6-17(7-5-16)25-24(31)27-10-8-26(9-11-27)22-15(3)21-19(29)12-18(28)13-20(21)32-23(22)30/h4-7,12-14,28-29H,8-11H2,1-3H3,(H,25,31)	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Medical Sciences and Peking Union Medical College Curated by ChEMBL					Assay Description Displacement of FITC-CKLF1-C27 from human CCR4 receptor expressed in human HEK293 cells				J Med Chem 53: 1741-54 (2010) Article DOI: 10.1021/jm901652p BindingDB Entry DOI: 10.7270/Q2Q81D6X
					More data for this Ligand-Target Pair