BDBM50307032 4-(5,7-Dihydroxy-4-methyl-2-oxo-2H-chromen-3-yl)-N-(2-phenoxyphenyl)piperazine-1-carboxamide::CHEMBL604330

SMILES: Cc1c(N2CCN(CC2)C(=O)Nc2ccccc2Oc2ccccc2)c(=O)oc2cc(O)cc(O)c12

InChI Key: InChIKey=LMBVYTOLFGLOFG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50307032   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 4 (CCR4) (Homo sapiens (Human))	BDBM50307032 (4-(5,7-Dihydroxy-4-methyl-2-oxo-2H-chromen-3-yl)-N...) Show SMILES Cc1c(N2CCN(CC2)C(=O)Nc2ccccc2Oc2ccccc2)c(=O)oc2cc(O)cc(O)c12 Show InChI InChI=1S/C27H25N3O6/c1-17-24-21(32)15-18(31)16-23(24)36-26(33)25(17)29-11-13-30(14-12-29)27(34)28-20-9-5-6-10-22(20)35-19-7-3-2-4-8-19/h2-10,15-16,31-32H,11-14H2,1H3,(H,28,34)	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Medical Sciences and Peking Union Medical College Curated by ChEMBL					Assay Description Displacement of FITC-CKLF1-C27 from human CCR4 receptor expressed in human HEK293 cells				J Med Chem 53: 1741-54 (2010) Article DOI: 10.1021/jm901652p BindingDB Entry DOI: 10.7270/Q2Q81D6X
					More data for this Ligand-Target Pair