BDBM50307040 3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)-5,7-dihydroxy-4-methyl-2H-chromen-2-one::CHEMBL602474

SMILES: Cc1cccc(N2CCN(CC2)c2c(C)c3c(O)cc(O)cc3oc2=O)c1C

InChI Key: InChIKey=VSBCZFRLXMMGIS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50307040   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 4 (CCR4) (Homo sapiens (Human))	BDBM50307040 (3-(4-(2,3-Dimethylphenyl)piperazin-1-yl)-5,7-dihyd...) Show SMILES Cc1cccc(N2CCN(CC2)c2c(C)c3c(O)cc(O)cc3oc2=O)c1C Show InChI InChI=1S/C22H24N2O4/c1-13-5-4-6-17(14(13)2)23-7-9-24(10-8-23)21-15(3)20-18(26)11-16(25)12-19(20)28-22(21)27/h4-6,11-12,25-26H,7-10H2,1-3H3	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.13E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Medical Sciences and Peking Union Medical College Curated by ChEMBL					Assay Description Displacement of FITC-CKLF1-C27 from human CCR4 receptor expressed in human HEK293 cells				J Med Chem 53: 1741-54 (2010) Article DOI: 10.1021/jm901652p BindingDB Entry DOI: 10.7270/Q2Q81D6X
					More data for this Ligand-Target Pair