BDBM50307041 3-(4-(2-Ethylbutyl)piperazin-1-yl)-5,7-dihydroxy-4-methyl-2H-chromen-2-one::CHEMBL589276

SMILES: CCC(CC)CN1CCN(CC1)c1c(C)c2c(O)cc(O)cc2oc1=O

InChI Key: InChIKey=TZJVPFPBBNHJGP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50307041   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 4 (CCR4) (Homo sapiens (Human))	BDBM50307041 (3-(4-(2-Ethylbutyl)piperazin-1-yl)-5,7-dihydroxy-4...) Show SMILES CCC(CC)CN1CCN(CC1)c1c(C)c2c(O)cc(O)cc2oc1=O Show InChI InChI=1S/C20H28N2O4/c1-4-14(5-2)12-21-6-8-22(9-7-21)19-13(3)18-16(24)10-15(23)11-17(18)26-20(19)25/h10-11,14,23-24H,4-9,12H2,1-3H3	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Medical Sciences and Peking Union Medical College Curated by ChEMBL					Assay Description Displacement of FITC-CKLF1-C27 from human CCR4 receptor expressed in human HEK293 cells				J Med Chem 53: 1741-54 (2010) Article DOI: 10.1021/jm901652p BindingDB Entry DOI: 10.7270/Q2Q81D6X
					More data for this Ligand-Target Pair