BDBM50307046 5,7-Dimethoxy-4-methyl-3-(4-methylpiperazin-1-yl)-2H-chromen-2-one::CHEMBL589521

SMILES: COc1cc(OC)c2c(C)c(N3CCN(C)CC3)c(=O)oc2c1

InChI Key: InChIKey=FTBBXYKBHDWXDK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50307046   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 4 (CCR4) (Homo sapiens (Human))	BDBM50307046 (5,7-Dimethoxy-4-methyl-3-(4-methylpiperazin-1-yl)-...) Show SMILES COc1cc(OC)c2c(C)c(N3CCN(C)CC3)c(=O)oc2c1 Show InChI InChI=1S/C17H22N2O4/c1-11-15-13(22-4)9-12(21-3)10-14(15)23-17(20)16(11)19-7-5-18(2)6-8-19/h9-10H,5-8H2,1-4H3	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	478	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Medical Sciences and Peking Union Medical College Curated by ChEMBL					Assay Description Displacement of FITC-CKLF1-C27 from human CCR4 receptor expressed in human HEK293 cells				J Med Chem 53: 1741-54 (2010) Article DOI: 10.1021/jm901652p BindingDB Entry DOI: 10.7270/Q2Q81D6X
					More data for this Ligand-Target Pair