BDBM50307047 7-(Dimethylamino)-4-methyl-3-(4-methylpiperazin-1-yl)-2Hchromen-2-one::CHEMBL600409

SMILES: CN(C)c1ccc2c(C)c(N3CCN(C)CC3)c(=O)oc2c1

InChI Key: InChIKey=OAAAHFCYRYRNQC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50307047   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 4 (CCR4) (Homo sapiens (Human))	BDBM50307047 (7-(Dimethylamino)-4-methyl-3-(4-methylpiperazin-1-...) Show SMILES CN(C)c1ccc2c(C)c(N3CCN(C)CC3)c(=O)oc2c1 Show InChI InChI=1S/C17H23N3O2/c1-12-14-6-5-13(18(2)3)11-15(14)22-17(21)16(12)20-9-7-19(4)8-10-20/h5-6,11H,7-10H2,1-4H3	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.76E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Medical Sciences and Peking Union Medical College Curated by ChEMBL					Assay Description Displacement of FITC-CKLF1-C27 from human CCR4 receptor expressed in human HEK293 cells				J Med Chem 53: 1741-54 (2010) Article DOI: 10.1021/jm901652p BindingDB Entry DOI: 10.7270/Q2Q81D6X
					More data for this Ligand-Target Pair