BDBM50307048 7-Methoxy-4-methyl-3-(4-methylpiperazin-1-yl)-2H-chromen-2-one::CHEMBL598339

SMILES: COc1ccc2c(C)c(N3CCN(C)CC3)c(=O)oc2c1

InChI Key: InChIKey=KYSJCKNWAUMJJL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50307048   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 4 (CCR4) (Homo sapiens (Human))	BDBM50307048 (7-Methoxy-4-methyl-3-(4-methylpiperazin-1-yl)-2H-c...) Show SMILES COc1ccc2c(C)c(N3CCN(C)CC3)c(=O)oc2c1 Show InChI InChI=1S/C16H20N2O3/c1-11-13-5-4-12(20-3)10-14(13)21-16(19)15(11)18-8-6-17(2)7-9-18/h4-5,10H,6-9H2,1-3H3	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.21E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Medical Sciences and Peking Union Medical College Curated by ChEMBL					Assay Description Displacement of FITC-CKLF1-C27 from human CCR4 receptor expressed in human HEK293 cells				J Med Chem 53: 1741-54 (2010) Article DOI: 10.1021/jm901652p BindingDB Entry DOI: 10.7270/Q2Q81D6X
					More data for this Ligand-Target Pair