BDBM50307052 4-Methyl-3-(4-methylpiperazin-1-yl)-7-(2-(thiophen-2-yl)ethoxy)-2H-chromen-2-one::CHEMBL603104

SMILES: CN1CCN(CC1)c1c(C)c2ccc(OCCc3cccs3)cc2oc1=O

InChI Key: InChIKey=OMRXGVUFCZLTMW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50307052   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 4 (CCR4) (Homo sapiens (Human))	BDBM50307052 (4-Methyl-3-(4-methylpiperazin-1-yl)-7-(2-(thiophen...) Show SMILES CN1CCN(CC1)c1c(C)c2ccc(OCCc3cccs3)cc2oc1=O Show InChI InChI=1S/C21H24N2O3S/c1-15-18-6-5-16(25-12-7-17-4-3-13-27-17)14-19(18)26-21(24)20(15)23-10-8-22(2)9-11-23/h3-6,13-14H,7-12H2,1-2H3	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	527	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Medical Sciences and Peking Union Medical College Curated by ChEMBL					Assay Description Displacement of FITC-CKLF1-C27 from human CCR4 receptor expressed in human HEK293 cells				J Med Chem 53: 1741-54 (2010) Article DOI: 10.1021/jm901652p BindingDB Entry DOI: 10.7270/Q2Q81D6X
					More data for this Ligand-Target Pair