BDBM50307055 4-Methyl-3-(4-methylpiperazin-1-yl)-7-(2-(pyrrolidin-1-yl)-ethoxy)-2H-chromen-2-one::CHEMBL600018

SMILES: CN1CCN(CC1)c1c(C)c2ccc(OCCN3CCCC3)cc2oc1=O

InChI Key: InChIKey=BXEZEVZDFCXRLP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50307055   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 4 (CCR4) (Homo sapiens (Human))	BDBM50307055 (4-Methyl-3-(4-methylpiperazin-1-yl)-7-(2-(pyrrolid...) Show SMILES CN1CCN(CC1)c1c(C)c2ccc(OCCN3CCCC3)cc2oc1=O Show InChI InChI=1S/C21H29N3O3/c1-16-18-6-5-17(26-14-13-23-7-3-4-8-23)15-19(18)27-21(25)20(16)24-11-9-22(2)10-12-24/h5-6,15H,3-4,7-14H2,1-2H3	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.51E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Medical Sciences and Peking Union Medical College Curated by ChEMBL					Assay Description Displacement of FITC-CKLF1-C27 from human CCR4 receptor expressed in human HEK293 cells				J Med Chem 53: 1741-54 (2010) Article DOI: 10.1021/jm901652p BindingDB Entry DOI: 10.7270/Q2Q81D6X
					More data for this Ligand-Target Pair