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SMILES: COCc1cc(\C=C2/NC(=S)NC2=O)ccc1OCCCOc1cc(C)cc(C)c1

InChI Key: InChIKey=KLKHAUGRSKRYTL-MOSHPQCFSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50307263   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Fibroblast growth factor receptor 1


(Homo sapiens (Human))		BDBM50307263
PNG
((Z)-5-(4-(3-(3,5-dimethylphenoxy)propoxy)-3-(metho...)
Show SMILES COCc1cc(\C=C2/NC(=S)NC2=O)ccc1OCCCOc1cc(C)cc(C)c1
Show InChI InChI=1S/C23H26N2O4S/c1-15-9-16(2)11-19(10-15)28-7-4-8-29-21-6-5-17(12-18(21)14-27-3)13-20-22(26)25-23(30)24-20/h5-6,9-13H,4,7-8,14H2,1-3H3,(H2,24,25,26,30)/b20-13-
PDB
MMDB

NCI pathway
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KEGG

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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.30E+6n/an/an/an/an/an/a



Yale University

Curated by ChEMBL


Assay Description
Inhibition of FGFR1

J Med Chem 53: 1662-72 (2010)


Article DOI: 10.1021/jm901386e
BindingDB Entry DOI: 10.7270/Q2T153RD
More data for this
Ligand-Target Pair