BDBM50307270 (3,5-Dimethyl-isoxazol-4-yl)-carbamic acid 2-(2-carbamimidoyl-benzo[b]thiophen-4-yloxy)-2-phenyl-ethyl ester::CHEMBL598169

SMILES: Cc1noc(C)c1NC(=O)OCC(Oc1cccc2sc(cc12)C(N)=N)c1ccccc1

InChI Key: InChIKey=WVTBQBGYKOVDJN-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50307270   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor IX (Homo sapiens (Human))	BDBM50307270 ((3,5-Dimethyl-isoxazol-4-yl)-carbamic acid 2-(2-ca...) Show SMILES Cc1noc(C)c1NC(=O)OCC(Oc1cccc2sc(cc12)C(N)=N)c1ccccc1 Show InChI InChI=1S/C23H22N4O4S/c1-13-21(14(2)31-27-13)26-23(28)29-12-18(15-7-4-3-5-8-15)30-17-9-6-10-19-16(17)11-20(32-19)22(24)25/h3-11,18H,12H2,1-2H3,(H3,24,25)(H,26,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Trigen Ltd. Curated by ChEMBL					Assay Description Inhibition of human recombinant factor 9a by amidolytic assay				J Med Chem 53: 1473-82 (2010) Article DOI: 10.1021/jm901476x BindingDB Entry DOI: 10.7270/Q2P84C0N
					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50307270 ((3,5-Dimethyl-isoxazol-4-yl)-carbamic acid 2-(2-ca...) Show SMILES Cc1noc(C)c1NC(=O)OCC(Oc1cccc2sc(cc12)C(N)=N)c1ccccc1 Show InChI InChI=1S/C23H22N4O4S/c1-13-21(14(2)31-27-13)26-23(28)29-12-18(15-7-4-3-5-8-15)30-17-9-6-10-19-16(17)11-20(32-19)22(24)25/h3-11,18H,12H2,1-2H3,(H3,24,25)(H,26,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	142	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Trigen Ltd. Curated by ChEMBL					Assay Description Inhibition of uPA				J Med Chem 53: 1473-82 (2010) Article DOI: 10.1021/jm901476x BindingDB Entry DOI: 10.7270/Q2P84C0N
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50307270 ((3,5-Dimethyl-isoxazol-4-yl)-carbamic acid 2-(2-ca...) Show SMILES Cc1noc(C)c1NC(=O)OCC(Oc1cccc2sc(cc12)C(N)=N)c1ccccc1 Show InChI InChI=1S/C23H22N4O4S/c1-13-21(14(2)31-27-13)26-23(28)29-12-18(15-7-4-3-5-8-15)30-17-9-6-10-19-16(17)11-20(32-19)22(24)25/h3-11,18H,12H2,1-2H3,(H3,24,25)(H,26,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	2.25E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Trigen Ltd. Curated by ChEMBL					Assay Description Inhibition of factor 10a by amidolytic assay				J Med Chem 53: 1473-82 (2010) Article DOI: 10.1021/jm901476x BindingDB Entry DOI: 10.7270/Q2P84C0N
					More data for this Ligand-Target Pair