BDBM50307272 (5-Methoxymethyl-2-methyl-2H-pyrazol-3-yl)-carbamic acid 2-(2-carbamimidoylbenzo[b]thiophen-4-yloxy)-2-phenyl-ethyl ester::CHEMBL601870

SMILES: COCc1cc(NC(=O)OCC(Oc2cccc3sc(cc23)C(N)=N)c2ccccc2)n(C)n1

InChI Key: InChIKey=ZKQPJCFASKEYAL-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50307272   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor IX (Homo sapiens (Human))	BDBM50307272 ((5-Methoxymethyl-2-methyl-2H-pyrazol-3-yl)-carbami...) Show SMILES COCc1cc(NC(=O)OCC(Oc2cccc3sc(cc23)C(N)=N)c2ccccc2)n(C)n1 Show InChI InChI=1S/C24H25N5O4S/c1-29-22(11-16(28-29)13-31-2)27-24(30)32-14-19(15-7-4-3-5-8-15)33-18-9-6-10-20-17(18)12-21(34-20)23(25)26/h3-12,19H,13-14H2,1-2H3,(H3,25,26)(H,27,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Trigen Ltd. Curated by ChEMBL					Assay Description Inhibition of human recombinant factor 9a by amidolytic assay				J Med Chem 53: 1473-82 (2010) Article DOI: 10.1021/jm901476x BindingDB Entry DOI: 10.7270/Q2P84C0N
					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50307272 ((5-Methoxymethyl-2-methyl-2H-pyrazol-3-yl)-carbami...) Show SMILES COCc1cc(NC(=O)OCC(Oc2cccc3sc(cc23)C(N)=N)c2ccccc2)n(C)n1 Show InChI InChI=1S/C24H25N5O4S/c1-29-22(11-16(28-29)13-31-2)27-24(30)32-14-19(15-7-4-3-5-8-15)33-18-9-6-10-20-17(18)12-21(34-20)23(25)26/h3-12,19H,13-14H2,1-2H3,(H3,25,26)(H,27,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	109	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Trigen Ltd. Curated by ChEMBL					Assay Description Inhibition of uPA				J Med Chem 53: 1473-82 (2010) Article DOI: 10.1021/jm901476x BindingDB Entry DOI: 10.7270/Q2P84C0N
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50307272 ((5-Methoxymethyl-2-methyl-2H-pyrazol-3-yl)-carbami...) Show SMILES COCc1cc(NC(=O)OCC(Oc2cccc3sc(cc23)C(N)=N)c2ccccc2)n(C)n1 Show InChI InChI=1S/C24H25N5O4S/c1-29-22(11-16(28-29)13-31-2)27-24(30)32-14-19(15-7-4-3-5-8-15)33-18-9-6-10-20-17(18)12-21(34-20)23(25)26/h3-12,19H,13-14H2,1-2H3,(H3,25,26)(H,27,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.56E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Trigen Ltd. Curated by ChEMBL					Assay Description Inhibition of factor 10a by amidolytic assay				J Med Chem 53: 1473-82 (2010) Article DOI: 10.1021/jm901476x BindingDB Entry DOI: 10.7270/Q2P84C0N
					More data for this Ligand-Target Pair