Found 3 hits for monomerid = 50307277 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Coagulation factor IX
(Homo sapiens (Human)) | BDBM50307277
(CHEMBL604954 | [5-(Isopropylamino-methyl)-1,3-dime...)Show SMILES CC(C)NCc1c(NC(=O)OCC(Oc2cccc3sc(cc23)C(N)=N)c2ccccc2)c(C)nn1C Show InChI InChI=1S/C27H32N6O3S/c1-16(2)30-14-20-25(17(3)32-33(20)4)31-27(34)35-15-22(18-9-6-5-7-10-18)36-21-11-8-12-23-19(21)13-24(37-23)26(28)29/h5-13,16,22,30H,14-15H2,1-4H3,(H3,28,29)(H,31,34) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description Inhibition of human recombinant factor 9a by amidolytic assay |
J Med Chem 53: 1473-82 (2010)
Article DOI: 10.1021/jm901476x BindingDB Entry DOI: 10.7270/Q2P84C0N |
More data for this Ligand-Target Pair | |
Urokinase-type plasminogen activator
(Homo sapiens (Human)) | BDBM50307277
(CHEMBL604954 | [5-(Isopropylamino-methyl)-1,3-dime...)Show SMILES CC(C)NCc1c(NC(=O)OCC(Oc2cccc3sc(cc23)C(N)=N)c2ccccc2)c(C)nn1C Show InChI InChI=1S/C27H32N6O3S/c1-16(2)30-14-20-25(17(3)32-33(20)4)31-27(34)35-15-22(18-9-6-5-7-10-18)36-21-11-8-12-23-19(21)13-24(37-23)26(28)29/h5-13,16,22,30H,14-15H2,1-4H3,(H3,28,29)(H,31,34) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 151 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description Inhibition of uPA |
J Med Chem 53: 1473-82 (2010)
Article DOI: 10.1021/jm901476x BindingDB Entry DOI: 10.7270/Q2P84C0N |
More data for this Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50307277
(CHEMBL604954 | [5-(Isopropylamino-methyl)-1,3-dime...)Show SMILES CC(C)NCc1c(NC(=O)OCC(Oc2cccc3sc(cc23)C(N)=N)c2ccccc2)c(C)nn1C Show InChI InChI=1S/C27H32N6O3S/c1-16(2)30-14-20-25(17(3)32-33(20)4)31-27(34)35-15-22(18-9-6-5-7-10-18)36-21-11-8-12-23-19(21)13-24(37-23)26(28)29/h5-13,16,22,30H,14-15H2,1-4H3,(H3,28,29)(H,31,34) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 1.63E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description Inhibition of factor 10a by amidolytic assay |
J Med Chem 53: 1473-82 (2010)
Article DOI: 10.1021/jm901476x BindingDB Entry DOI: 10.7270/Q2P84C0N |
More data for this Ligand-Target Pair | |