Found 3 hits for monomerid = 50307278 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Coagulation factor IX
(Homo sapiens (Human)) | BDBM50307278
(CHEMBL602083 | Phenyl-carbamic acid 2-(2-carbamimi...)Show SMILES NC(=N)c1cc2c(OC(COC(=O)Nc3ccccc3)c3ccccc3)cc(F)cc2s1 Show InChI InChI=1S/C24H20FN3O3S/c25-16-11-19(18-13-22(23(26)27)32-21(18)12-16)31-20(15-7-3-1-4-8-15)14-30-24(29)28-17-9-5-2-6-10-17/h1-13,20H,14H2,(H3,26,27)(H,28,29) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 15.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description Inhibition of human recombinant factor 9a by amidolytic assay |
J Med Chem 53: 1473-82 (2010)
Article DOI: 10.1021/jm901476x BindingDB Entry DOI: 10.7270/Q2P84C0N |
More data for this Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50307278
(CHEMBL602083 | Phenyl-carbamic acid 2-(2-carbamimi...)Show SMILES NC(=N)c1cc2c(OC(COC(=O)Nc3ccccc3)c3ccccc3)cc(F)cc2s1 Show InChI InChI=1S/C24H20FN3O3S/c25-16-11-19(18-13-22(23(26)27)32-21(18)12-16)31-20(15-7-3-1-4-8-15)14-30-24(29)28-17-9-5-2-6-10-17/h1-13,20H,14H2,(H3,26,27)(H,28,29) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 1.59E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description Inhibition of factor 10a by amidolytic assay |
J Med Chem 53: 1473-82 (2010)
Article DOI: 10.1021/jm901476x BindingDB Entry DOI: 10.7270/Q2P84C0N |
More data for this Ligand-Target Pair | |
Urokinase-type plasminogen activator
(Homo sapiens (Human)) | BDBM50307278
(CHEMBL602083 | Phenyl-carbamic acid 2-(2-carbamimi...)Show SMILES NC(=N)c1cc2c(OC(COC(=O)Nc3ccccc3)c3ccccc3)cc(F)cc2s1 Show InChI InChI=1S/C24H20FN3O3S/c25-16-11-19(18-13-22(23(26)27)32-21(18)12-16)31-20(15-7-3-1-4-8-15)14-30-24(29)28-17-9-5-2-6-10-17/h1-13,20H,14H2,(H3,26,27)(H,28,29) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 2.12E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description Inhibition of uPA |
J Med Chem 53: 1473-82 (2010)
Article DOI: 10.1021/jm901476x BindingDB Entry DOI: 10.7270/Q2P84C0N |
More data for this Ligand-Target Pair | |