BDBM50307279 (2-Aminomethyl-phenyl)-carbamic acid 2-(2-carbamimidoyl-6-fluorobenzo[b]thiophen-4-yloxy)-2-phenyl-ethyl ester::CHEMBL601241

SMILES: NCc1ccccc1NC(=O)OCC(Oc1cc(F)cc2sc(cc12)C(N)=N)c1ccccc1

InChI Key: InChIKey=DDPUNJKAKZZDPA-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50307279   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor IX (Homo sapiens (Human))	BDBM50307279 ((2-Aminomethyl-phenyl)-carbamic acid 2-(2-carbamim...) Show SMILES NCc1ccccc1NC(=O)OCC(Oc1cc(F)cc2sc(cc12)C(N)=N)c1ccccc1 Show InChI InChI=1S/C25H23FN4O3S/c26-17-10-20(18-12-23(24(28)29)34-22(18)11-17)33-21(15-6-2-1-3-7-15)14-32-25(31)30-19-9-5-4-8-16(19)13-27/h1-12,21H,13-14,27H2,(H3,28,29)(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Trigen Ltd. Curated by ChEMBL					Assay Description Inhibition of human recombinant factor 9a by amidolytic assay				J Med Chem 53: 1473-82 (2010) Article DOI: 10.1021/jm901476x BindingDB Entry DOI: 10.7270/Q2P84C0N
					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50307279 ((2-Aminomethyl-phenyl)-carbamic acid 2-(2-carbamim...) Show SMILES NCc1ccccc1NC(=O)OCC(Oc1cc(F)cc2sc(cc12)C(N)=N)c1ccccc1 Show InChI InChI=1S/C25H23FN4O3S/c26-17-10-20(18-12-23(24(28)29)34-22(18)11-17)33-21(15-6-2-1-3-7-15)14-32-25(31)30-19-9-5-4-8-16(19)13-27/h1-12,21H,13-14,27H2,(H3,28,29)(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	828	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Trigen Ltd. Curated by ChEMBL					Assay Description Inhibition of uPA				J Med Chem 53: 1473-82 (2010) Article DOI: 10.1021/jm901476x BindingDB Entry DOI: 10.7270/Q2P84C0N
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50307279 ((2-Aminomethyl-phenyl)-carbamic acid 2-(2-carbamim...) Show SMILES NCc1ccccc1NC(=O)OCC(Oc1cc(F)cc2sc(cc12)C(N)=N)c1ccccc1 Show InChI InChI=1S/C25H23FN4O3S/c26-17-10-20(18-12-23(24(28)29)34-22(18)11-17)33-21(15-6-2-1-3-7-15)14-32-25(31)30-19-9-5-4-8-16(19)13-27/h1-12,21H,13-14,27H2,(H3,28,29)(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.12E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Trigen Ltd. Curated by ChEMBL					Assay Description Inhibition of factor 10a by amidolytic assay				J Med Chem 53: 1473-82 (2010) Article DOI: 10.1021/jm901476x BindingDB Entry DOI: 10.7270/Q2P84C0N
					More data for this Ligand-Target Pair