BDBM50307280 (2-Dimethylaminomethyl-phenyl)-carbamic acid 2-(2-carbamimidoyl-6-fluorobenzo[b]thiophen-4-yloxy)-2-phenyl-ethyl ester::CHEMBL603242

SMILES: CN(C)Cc1ccccc1NC(=O)OCC(Oc1cc(F)cc2sc(cc12)C(N)=N)c1ccccc1

InChI Key: InChIKey=SMMZRDAVBONMHW-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50307280   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor IX (Homo sapiens (Human))	BDBM50307280 ((2-Dimethylaminomethyl-phenyl)-carbamic acid 2-(2-...) Show SMILES CN(C)Cc1ccccc1NC(=O)OCC(Oc1cc(F)cc2sc(cc12)C(N)=N)c1ccccc1 Show InChI InChI=1S/C27H27FN4O3S/c1-32(2)15-18-10-6-7-11-21(18)31-27(33)34-16-23(17-8-4-3-5-9-17)35-22-12-19(28)13-24-20(22)14-25(36-24)26(29)30/h3-14,23H,15-16H2,1-2H3,(H3,29,30)(H,31,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	8.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Trigen Ltd. Curated by ChEMBL					Assay Description Inhibition of human recombinant factor 9a by amidolytic assay				J Med Chem 53: 1473-82 (2010) Article DOI: 10.1021/jm901476x BindingDB Entry DOI: 10.7270/Q2P84C0N
					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50307280 ((2-Dimethylaminomethyl-phenyl)-carbamic acid 2-(2-...) Show SMILES CN(C)Cc1ccccc1NC(=O)OCC(Oc1cc(F)cc2sc(cc12)C(N)=N)c1ccccc1 Show InChI InChI=1S/C27H27FN4O3S/c1-32(2)15-18-10-6-7-11-21(18)31-27(33)34-16-23(17-8-4-3-5-9-17)35-22-12-19(28)13-24-20(22)14-25(36-24)26(29)30/h3-14,23H,15-16H2,1-2H3,(H3,29,30)(H,31,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	940	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Trigen Ltd. Curated by ChEMBL					Assay Description Inhibition of uPA				J Med Chem 53: 1473-82 (2010) Article DOI: 10.1021/jm901476x BindingDB Entry DOI: 10.7270/Q2P84C0N
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50307280 ((2-Dimethylaminomethyl-phenyl)-carbamic acid 2-(2-...) Show SMILES CN(C)Cc1ccccc1NC(=O)OCC(Oc1cc(F)cc2sc(cc12)C(N)=N)c1ccccc1 Show InChI InChI=1S/C27H27FN4O3S/c1-32(2)15-18-10-6-7-11-21(18)31-27(33)34-16-23(17-8-4-3-5-9-17)35-22-12-19(28)13-24-20(22)14-25(36-24)26(29)30/h3-14,23H,15-16H2,1-2H3,(H3,29,30)(H,31,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.36E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Trigen Ltd. Curated by ChEMBL					Assay Description Inhibition of factor 10a by amidolytic assay				J Med Chem 53: 1473-82 (2010) Article DOI: 10.1021/jm901476x BindingDB Entry DOI: 10.7270/Q2P84C0N
					More data for this Ligand-Target Pair