Found 3 hits for monomerid = 50307287 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50307287
(2-(2-Carbamimidoyl-benzo[b]thiophen-4-yloxy)-N-(2-...)Show SMILES COc1ccccc1NC(=O)C(Oc1cccc2sc(cc12)C(N)=N)c1ccccc1 Show InChI InChI=1S/C24H21N3O3S/c1-29-19-11-6-5-10-17(19)27-24(28)22(15-8-3-2-4-9-15)30-18-12-7-13-20-16(18)14-21(31-20)23(25)26/h2-14,22H,1H3,(H3,25,26)(H,27,28) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description Inhibition of factor 10a by amidolytic assay |
J Med Chem 53: 1473-82 (2010)
Article DOI: 10.1021/jm901476x BindingDB Entry DOI: 10.7270/Q2P84C0N |
More data for this Ligand-Target Pair | |
Urokinase-type plasminogen activator
(Homo sapiens (Human)) | BDBM50307287
(2-(2-Carbamimidoyl-benzo[b]thiophen-4-yloxy)-N-(2-...)Show SMILES COc1ccccc1NC(=O)C(Oc1cccc2sc(cc12)C(N)=N)c1ccccc1 Show InChI InChI=1S/C24H21N3O3S/c1-29-19-11-6-5-10-17(19)27-24(28)22(15-8-3-2-4-9-15)30-18-12-7-13-20-16(18)14-21(31-20)23(25)26/h2-14,22H,1H3,(H3,25,26)(H,27,28) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description Inhibition of uPA |
J Med Chem 53: 1473-82 (2010)
Article DOI: 10.1021/jm901476x BindingDB Entry DOI: 10.7270/Q2P84C0N |
More data for this Ligand-Target Pair | |
Coagulation factor IX
(Homo sapiens (Human)) | BDBM50307287
(2-(2-Carbamimidoyl-benzo[b]thiophen-4-yloxy)-N-(2-...)Show SMILES COc1ccccc1NC(=O)C(Oc1cccc2sc(cc12)C(N)=N)c1ccccc1 Show InChI InChI=1S/C24H21N3O3S/c1-29-19-11-6-5-10-17(19)27-24(28)22(15-8-3-2-4-9-15)30-18-12-7-13-20-16(18)14-21(31-20)23(25)26/h2-14,22H,1H3,(H3,25,26)(H,27,28) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 140 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description Inhibition of human recombinant factor 9a by amidolytic assay |
J Med Chem 53: 1473-82 (2010)
Article DOI: 10.1021/jm901476x BindingDB Entry DOI: 10.7270/Q2P84C0N |
More data for this Ligand-Target Pair | |