BDBM50307295 4-(2-Benzylamino-1-phenyl-ethoxy)-benzo[b]thiophene-2-carboxamidine::CHEMBL599001

SMILES: NC(=N)c1cc2c(OC(CNCc3ccccc3)c3ccccc3)cccc2s1

InChI Key: InChIKey=NFJBOMRZPXKWOS-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50307295   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor IX (Homo sapiens (Human))	BDBM50307295 (4-(2-Benzylamino-1-phenyl-ethoxy)-benzo[b]thiophen...) Show SMILES NC(=N)c1cc2c(OC(CNCc3ccccc3)c3ccccc3)cccc2s1 Show InChI InChI=1S/C24H23N3OS/c25-24(26)23-14-19-20(12-7-13-22(19)29-23)28-21(18-10-5-2-6-11-18)16-27-15-17-8-3-1-4-9-17/h1-14,21,27H,15-16H2,(H3,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Trigen Ltd. Curated by ChEMBL					Assay Description Inhibition of human recombinant factor 9a by amidolytic assay				J Med Chem 53: 1473-82 (2010) Article DOI: 10.1021/jm901476x BindingDB Entry DOI: 10.7270/Q2P84C0N
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50307295 (4-(2-Benzylamino-1-phenyl-ethoxy)-benzo[b]thiophen...) Show SMILES NC(=N)c1cc2c(OC(CNCc3ccccc3)c3ccccc3)cccc2s1 Show InChI InChI=1S/C24H23N3OS/c25-24(26)23-14-19-20(12-7-13-22(19)29-23)28-21(18-10-5-2-6-11-18)16-27-15-17-8-3-1-4-9-17/h1-14,21,27H,15-16H2,(H3,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	250	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Trigen Ltd. Curated by ChEMBL					Assay Description Inhibition of factor 10a by amidolytic assay				J Med Chem 53: 1473-82 (2010) Article DOI: 10.1021/jm901476x BindingDB Entry DOI: 10.7270/Q2P84C0N
					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50307295 (4-(2-Benzylamino-1-phenyl-ethoxy)-benzo[b]thiophen...) Show SMILES NC(=N)c1cc2c(OC(CNCc3ccccc3)c3ccccc3)cccc2s1 Show InChI InChI=1S/C24H23N3OS/c25-24(26)23-14-19-20(12-7-13-22(19)29-23)28-21(18-10-5-2-6-11-18)16-27-15-17-8-3-1-4-9-17/h1-14,21,27H,15-16H2,(H3,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	310	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Trigen Ltd. Curated by ChEMBL					Assay Description Inhibition of uPA				J Med Chem 53: 1473-82 (2010) Article DOI: 10.1021/jm901476x BindingDB Entry DOI: 10.7270/Q2P84C0N
					More data for this Ligand-Target Pair