Found 3 hits for monomerid = 50307296 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Coagulation factor IX
(Homo sapiens (Human)) | BDBM50307296
(CHEMBL597370 | [2-(2-Carbamimidoyl-benzo[b]thiophe...)Show SMILES NC(=N)c1cc2c(OC(CNC(=O)Oc3ccccc3)c3ccccc3)cccc2s1 Show InChI InChI=1S/C24H21N3O3S/c25-23(26)22-14-18-19(12-7-13-21(18)31-22)30-20(16-8-3-1-4-9-16)15-27-24(28)29-17-10-5-2-6-11-17/h1-14,20H,15H2,(H3,25,26)(H,27,28) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 50 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description Inhibition of human recombinant factor 9a by amidolytic assay |
J Med Chem 53: 1473-82 (2010)
Article DOI: 10.1021/jm901476x BindingDB Entry DOI: 10.7270/Q2P84C0N |
More data for this Ligand-Target Pair | |
Urokinase-type plasminogen activator
(Homo sapiens (Human)) | BDBM50307296
(CHEMBL597370 | [2-(2-Carbamimidoyl-benzo[b]thiophe...)Show SMILES NC(=N)c1cc2c(OC(CNC(=O)Oc3ccccc3)c3ccccc3)cccc2s1 Show InChI InChI=1S/C24H21N3O3S/c25-23(26)22-14-18-19(12-7-13-21(18)31-22)30-20(16-8-3-1-4-9-16)15-27-24(28)29-17-10-5-2-6-11-17/h1-14,20H,15H2,(H3,25,26)(H,27,28) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 85 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description Inhibition of uPA |
J Med Chem 53: 1473-82 (2010)
Article DOI: 10.1021/jm901476x BindingDB Entry DOI: 10.7270/Q2P84C0N |
More data for this Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50307296
(CHEMBL597370 | [2-(2-Carbamimidoyl-benzo[b]thiophe...)Show SMILES NC(=N)c1cc2c(OC(CNC(=O)Oc3ccccc3)c3ccccc3)cccc2s1 Show InChI InChI=1S/C24H21N3O3S/c25-23(26)22-14-18-19(12-7-13-21(18)31-22)30-20(16-8-3-1-4-9-16)15-27-24(28)29-17-10-5-2-6-11-17/h1-14,20H,15H2,(H3,25,26)(H,27,28) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 560 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description Inhibition of factor 10a by amidolytic assay |
J Med Chem 53: 1473-82 (2010)
Article DOI: 10.1021/jm901476x BindingDB Entry DOI: 10.7270/Q2P84C0N |
More data for this Ligand-Target Pair | |