BDBM50307299 CHEMBL599415::Methyl-carbamic acid 2-(2-carbamimidoyl-benzo[b]thiophen-4-yloxy)-2-phenylethylester

SMILES: CNC(=O)OCC(Oc1cccc2sc(cc12)C(N)=N)c1ccccc1

InChI Key: InChIKey=IPIVVFVBOCKVJN-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50307299   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor IX (Homo sapiens (Human))	BDBM50307299 (CHEMBL599415 | Methyl-carbamic acid 2-(2-carbamimi...) Show SMILES CNC(=O)OCC(Oc1cccc2sc(cc12)C(N)=N)c1ccccc1 Show InChI InChI=1S/C19H19N3O3S/c1-22-19(23)24-11-15(12-6-3-2-4-7-12)25-14-8-5-9-16-13(14)10-17(26-16)18(20)21/h2-10,15H,11H2,1H3,(H3,20,21)(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	97	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Trigen Ltd. Curated by ChEMBL					Assay Description Inhibition of human recombinant factor 9a by amidolytic assay				J Med Chem 53: 1473-82 (2010) Article DOI: 10.1021/jm901476x BindingDB Entry DOI: 10.7270/Q2P84C0N
					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50307299 (CHEMBL599415 | Methyl-carbamic acid 2-(2-carbamimi...) Show SMILES CNC(=O)OCC(Oc1cccc2sc(cc12)C(N)=N)c1ccccc1 Show InChI InChI=1S/C19H19N3O3S/c1-22-19(23)24-11-15(12-6-3-2-4-7-12)25-14-8-5-9-16-13(14)10-17(26-16)18(20)21/h2-10,15H,11H2,1H3,(H3,20,21)(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Trigen Ltd. Curated by ChEMBL					Assay Description Inhibition of uPA				J Med Chem 53: 1473-82 (2010) Article DOI: 10.1021/jm901476x BindingDB Entry DOI: 10.7270/Q2P84C0N
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50307299 (CHEMBL599415 | Methyl-carbamic acid 2-(2-carbamimi...) Show SMILES CNC(=O)OCC(Oc1cccc2sc(cc12)C(N)=N)c1ccccc1 Show InChI InChI=1S/C19H19N3O3S/c1-22-19(23)24-11-15(12-6-3-2-4-7-12)25-14-8-5-9-16-13(14)10-17(26-16)18(20)21/h2-10,15H,11H2,1H3,(H3,20,21)(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Trigen Ltd. Curated by ChEMBL					Assay Description Inhibition of factor 10a by amidolytic assay				J Med Chem 53: 1473-82 (2010) Article DOI: 10.1021/jm901476x BindingDB Entry DOI: 10.7270/Q2P84C0N
					More data for this Ligand-Target Pair