BDBM50307310 CHEMBL597143::[4-(2-Dimethylamino-ethoxy)-phenyl]-carbamic acid 2-(2-carbamimidoylbenzo[b]thiophen-4-yloxy)-2-phenyl-ethyl ester

SMILES: CN(C)CCOc1ccc(NC(=O)OCC(Oc2cccc3sc(cc23)C(N)=N)c2ccccc2)cc1

InChI Key: InChIKey=DLXQMELVHFKJOP-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50307310   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor IX (Homo sapiens (Human))	BDBM50307310 (CHEMBL597143 | [4-(2-Dimethylamino-ethoxy)-phenyl]...) Show SMILES CN(C)CCOc1ccc(NC(=O)OCC(Oc2cccc3sc(cc23)C(N)=N)c2ccccc2)cc1 Show InChI InChI=1S/C28H30N4O4S/c1-32(2)15-16-34-21-13-11-20(12-14-21)31-28(33)35-18-24(19-7-4-3-5-8-19)36-23-9-6-10-25-22(23)17-26(37-25)27(29)30/h3-14,17,24H,15-16,18H2,1-2H3,(H3,29,30)(H,31,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Trigen Ltd. Curated by ChEMBL					Assay Description Inhibition of human recombinant factor 9a by amidolytic assay				J Med Chem 53: 1473-82 (2010) Article DOI: 10.1021/jm901476x BindingDB Entry DOI: 10.7270/Q2P84C0N
					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50307310 (CHEMBL597143 | [4-(2-Dimethylamino-ethoxy)-phenyl]...) Show SMILES CN(C)CCOc1ccc(NC(=O)OCC(Oc2cccc3sc(cc23)C(N)=N)c2ccccc2)cc1 Show InChI InChI=1S/C28H30N4O4S/c1-32(2)15-16-34-21-13-11-20(12-14-21)31-28(33)35-18-24(19-7-4-3-5-8-19)36-23-9-6-10-25-22(23)17-26(37-25)27(29)30/h3-14,17,24H,15-16,18H2,1-2H3,(H3,29,30)(H,31,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	201	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Trigen Ltd. Curated by ChEMBL					Assay Description Inhibition of uPA				J Med Chem 53: 1473-82 (2010) Article DOI: 10.1021/jm901476x BindingDB Entry DOI: 10.7270/Q2P84C0N
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50307310 (CHEMBL597143 | [4-(2-Dimethylamino-ethoxy)-phenyl]...) Show SMILES CN(C)CCOc1ccc(NC(=O)OCC(Oc2cccc3sc(cc23)C(N)=N)c2ccccc2)cc1 Show InChI InChI=1S/C28H30N4O4S/c1-32(2)15-16-34-21-13-11-20(12-14-21)31-28(33)35-18-24(19-7-4-3-5-8-19)36-23-9-6-10-25-22(23)17-26(37-25)27(29)30/h3-14,17,24H,15-16,18H2,1-2H3,(H3,29,30)(H,31,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	872	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Trigen Ltd. Curated by ChEMBL					Assay Description Inhibition of factor 10a by amidolytic assay				J Med Chem 53: 1473-82 (2010) Article DOI: 10.1021/jm901476x BindingDB Entry DOI: 10.7270/Q2P84C0N
					More data for this Ligand-Target Pair