Found 3 hits for monomerid = 50307311 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Coagulation factor IX
(Homo sapiens (Human)) | BDBM50307311
(CHEMBL597144 | [4-(4-Methyl-piperazin-1-ylmethyl)-...)Show SMILES CN1CCN(Cc2ccc(NC(=O)OCC(Oc3cccc4sc(cc34)C(N)=N)c3ccccc3)cc2)CC1 Show InChI InChI=1S/C30H33N5O3S/c1-34-14-16-35(17-15-34)19-21-10-12-23(13-11-21)33-30(36)37-20-26(22-6-3-2-4-7-22)38-25-8-5-9-27-24(25)18-28(39-27)29(31)32/h2-13,18,26H,14-17,19-20H2,1H3,(H3,31,32)(H,33,36) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description Inhibition of human recombinant factor 9a by amidolytic assay |
J Med Chem 53: 1473-82 (2010)
Article DOI: 10.1021/jm901476x BindingDB Entry DOI: 10.7270/Q2P84C0N |
More data for this Ligand-Target Pair | |
Urokinase-type plasminogen activator
(Homo sapiens (Human)) | BDBM50307311
(CHEMBL597144 | [4-(4-Methyl-piperazin-1-ylmethyl)-...)Show SMILES CN1CCN(Cc2ccc(NC(=O)OCC(Oc3cccc4sc(cc34)C(N)=N)c3ccccc3)cc2)CC1 Show InChI InChI=1S/C30H33N5O3S/c1-34-14-16-35(17-15-34)19-21-10-12-23(13-11-21)33-30(36)37-20-26(22-6-3-2-4-7-22)38-25-8-5-9-27-24(25)18-28(39-27)29(31)32/h2-13,18,26H,14-17,19-20H2,1H3,(H3,31,32)(H,33,36) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 201 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description Inhibition of uPA |
J Med Chem 53: 1473-82 (2010)
Article DOI: 10.1021/jm901476x BindingDB Entry DOI: 10.7270/Q2P84C0N |
More data for this Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50307311
(CHEMBL597144 | [4-(4-Methyl-piperazin-1-ylmethyl)-...)Show SMILES CN1CCN(Cc2ccc(NC(=O)OCC(Oc3cccc4sc(cc34)C(N)=N)c3ccccc3)cc2)CC1 Show InChI InChI=1S/C30H33N5O3S/c1-34-14-16-35(17-15-34)19-21-10-12-23(13-11-21)33-30(36)37-20-26(22-6-3-2-4-7-22)38-25-8-5-9-27-24(25)18-28(39-27)29(31)32/h2-13,18,26H,14-17,19-20H2,1H3,(H3,31,32)(H,33,36) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 1.56E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description Inhibition of factor 10a by amidolytic assay |
J Med Chem 53: 1473-82 (2010)
Article DOI: 10.1021/jm901476x BindingDB Entry DOI: 10.7270/Q2P84C0N |
More data for this Ligand-Target Pair | |