Found 3 hits for monomerid = 50307315 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Coagulation factor IX
(Homo sapiens (Human)) | BDBM50307315
((2-Dimethylaminomethyl-phenyl)-carbamic acid 2-(2-...)Show SMILES CN(C)Cc1ccccc1NC(=O)OCC(Oc1cccc2sc(cc12)C(N)=N)c1ccccc1 Show InChI InChI=1S/C27H28N4O3S/c1-31(2)16-19-11-6-7-12-21(19)30-27(32)33-17-23(18-9-4-3-5-10-18)34-22-13-8-14-24-20(22)15-25(35-24)26(28)29/h3-15,23H,16-17H2,1-2H3,(H3,28,29)(H,30,32) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description Inhibition of human recombinant factor 9a by amidolytic assay |
J Med Chem 53: 1473-82 (2010)
Article DOI: 10.1021/jm901476x BindingDB Entry DOI: 10.7270/Q2P84C0N |
More data for this Ligand-Target Pair | |
Urokinase-type plasminogen activator
(Homo sapiens (Human)) | BDBM50307315
((2-Dimethylaminomethyl-phenyl)-carbamic acid 2-(2-...)Show SMILES CN(C)Cc1ccccc1NC(=O)OCC(Oc1cccc2sc(cc12)C(N)=N)c1ccccc1 Show InChI InChI=1S/C27H28N4O3S/c1-31(2)16-19-11-6-7-12-21(19)30-27(32)33-17-23(18-9-4-3-5-10-18)34-22-13-8-14-24-20(22)15-25(35-24)26(28)29/h3-15,23H,16-17H2,1-2H3,(H3,28,29)(H,30,32) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 609 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description Inhibition of uPA |
J Med Chem 53: 1473-82 (2010)
Article DOI: 10.1021/jm901476x BindingDB Entry DOI: 10.7270/Q2P84C0N |
More data for this Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50307315
((2-Dimethylaminomethyl-phenyl)-carbamic acid 2-(2-...)Show SMILES CN(C)Cc1ccccc1NC(=O)OCC(Oc1cccc2sc(cc12)C(N)=N)c1ccccc1 Show InChI InChI=1S/C27H28N4O3S/c1-31(2)16-19-11-6-7-12-21(19)30-27(32)33-17-23(18-9-4-3-5-10-18)34-22-13-8-14-24-20(22)15-25(35-24)26(28)29/h3-15,23H,16-17H2,1-2H3,(H3,28,29)(H,30,32) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 828 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Trigen Ltd.
Curated by ChEMBL
| Assay Description Inhibition of factor 10a by amidolytic assay |
J Med Chem 53: 1473-82 (2010)
Article DOI: 10.1021/jm901476x BindingDB Entry DOI: 10.7270/Q2P84C0N |
More data for this Ligand-Target Pair | |